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Evidence Explorer

LiveEvidence status is not proof of effectiveness, adoption, or endorsement.

Know exactly what the evidence supports—and what it does not.

Records are claim-specific. Evidence design, source authority, applicability, confidence, freshness, and decision priority remain visible instead of being flattened into a numeric score.

Primary/authoritativeFDA2026-06-16

AI-enabled medical devices: FDA maintains a non-comprehensive, periodically updated public list identifying AI-enabled medical devices authorized for marketing in the United States.

The list is explicitly non-comprehensive and periodically updated. Inclusion means FDA identified the device as AI-enabled and authorized it for marketing; omission proves neither lack of authorization nor lack of AI functionality, and inclusion does not establish comparative effectiveness, superiority, real-world performance, or adoption.

Primary/authoritativeCMS Innovation Center2026-07-20

ACCESS: CMS describes a ten-year model, rolling start dates, outcome-aligned payments, public reporting of aggregated risk-adjusted results, physician clinical oversight, clinical and data safeguards, and lifestyle/behavioral, diagnostic, medication, care-coordination, and technology-supported services.

The model is ongoing. Its design does not establish participant-specific effectiveness, final participation, coverage for every service, or future outcomes.

Primary/authoritativeCMS2026-07-29

Medicare App Library: CMS publishes a voluntary Medicare App Library participation and launch pathway for patient-facing apps, including three initial use cases and requirements concerning identity, CMS Aligned Network/FHIR connectivity, third-party review, CMS validation, and listing.

These are published participation and listing requirements, not proof that a particular app is clinically effective, CMS-endorsed, covered by Medicare, accepted into the library, or eligible for ACCESS payment. Requirements and listings can change. The pages checked also do not publish every product-specific evidence, usability, accessibility, equity, or technical threshold.

Primary/authoritativeCMS2026-08-17

ACCESS scale: CMS’s accepted-applicant page was updated August 17, 2026 and lists more than 150 accepted organizations. CMS says private payers representing 165 million members across Medicare Advantage, Medicaid, and commercial coverage have committed to align with the ACCESS payment approach, with many beginning in 2026. Inclusion on the accepted-applicant list is not CMS endorsement and does not guarantee final participation; participation remains contingent on Medicare enrollment, an executed agreement, final approval, and other requirements.

Accepted-applicant status is not CMS endorsement and does not guarantee final participation; participation remains contingent on Medicare enrollment, an executed agreement, final approval, and other requirements.

Primary/authoritativeFDA2026-08-21

TEMPO participants: FDA's maintained TEMPO participant table currently lists four participants: SonderMind, Inc. / SonderMind Adjunctive Care Application (SACA); Limbic Inc. / Unpacked; Cadence Solutions, Inc. / HypertensionOS; and Dexcom, Inc. / Dexcom Glucose Health Program.

FDA states that effectiveness for the participating intended uses has not yet been evaluated. Participation does not establish general FDA approval or clearance, Medicare coverage, endorsement, final CMS ACCESS participation, or scaled adoption. Reverify the maintained table before consequential use.

Primary/authoritativeFDA2026-04-28

Real-time clinical trials: FDA announced two initiated real-time clinical-trial proofs of concept that report endpoints and data signals to FDA in real time. Separately, FDA requested information on a proposed AI-enabled early-phase clinical-trial pilot.

The initiated reporting proofs do not establish comparative benefit or suitability for every trial. The separate AI-enabled pilot RFI closed June 29, 2026; the cited source does not establish a later selection or broader-pilot launch outcome.

Primary/authoritativeCMS + HHS OIG2026-05-14

RPM oversight: CMS highlighted OIG's finding that, in 2022 Medicare claims and Medicare Advantage encounter data, about 43% of enrollees receiving RPM lacked a claim or encounter record for at least one of three components.

The finding concerns 2022 claims and encounter data, not a current rate. CMS did not require providers to bill all three components, so no claim or encounter record does not prove a component was not furnished; the finding also does not establish inappropriate care or ineffectiveness.

Primary/authoritativeFDA2026-07-23

DHTs in drug development: FDA announced a funding opportunity that was open from July 20 through August 20, 2026, for projects exploring digital health technologies in drug development, including actigraphy, photography, and contactless sensors. The application window is closed. P4L is now watching for awardees, selected modalities, endpoint methods, validation work, and resulting guidance or precedents.

A historical funding opportunity does not establish an award, a validated digital measure, regulatory endpoint acceptance, guidance, or clinical benefit.

Evidence scope

Public corpus coverage

The current public corpus is a curated launch slice centered on authoritative program, policy, regulatory, standards, and R&D sources. It is not a comprehensive clinical evidence review of prevention, healthspan, longevity, interventions, biomarkers, technologies, outcomes, economics, or markets. Coverage is expanding by defined evidence track, with source type, population, method, uncertainty, applicability, and review status kept visible.

This public intelligence capability distinguishes sourced facts from P4L interpretation and preserves evidence and provenance links. It is not medical advice.

Evidence architecture

Eight evidence tracks

Expansion is organized through these tracks. Publication within a track does not imply comprehensive coverage.

Human outcomes

mortality, morbidity, function, quality of life, cognition, independence, adverse events, and patient experience.

Measures and endpoints

clinical outcome assessments, biomarkers, digital measures, functional tests, composite endpoints, validity, and meaningful change.

Prevention interventions

physical activity, nutrition and Food as Medicine, sleep, tobacco, alcohol, weight, hypertension, diabetes, mental health, vaccination, and screening.

Technologies and care models

diagnostics, wearables, remote monitoring, AI, digital therapeutics, MedTech, home-based care, and proactive-care workflows.

Implementation and adoption

workflow, workforce, procurement, usability, adherence, clinician trust, organizational readiness, scale, and sustainability.

Payment and economics

coverage, payment models, total cost, utilization, budget impact, incentives, and affordability.

Equity and access

population representation, disability, digital and rural access, language, affordability, differential performance, and distribution of benefit or burden.

Science and market landscape

trials, research programs, standards, companies, products, funding, partnerships, and competition, kept separate from evidence of benefit.