What this evidence supports
PROSPR funds seven teams to build healthspan measures and accelerated trials, with up to $144M over five years.
What it does not establish
The seven awards and funding ceiling are program facts, not evidence that the full ceiling will be paid or that an endpoint or intervention works. Continued funding is milestone-contingent, and the work remains investigational.
Answer-ready summary
ARPA-H PROSPR is explicitly building biomarkers, trial methods, and therapeutics aimed at extending healthspan.
Record details
- Decision priority
- Watch
- Current status
- Seven program awards listed · up to $144M over five years · milestone-contingent
- Evidence tracks
- Measures/endpoints · Science/market
- Source authority
- Primary/authoritative
- Source organization
- ARPA-H
- Evidence design
- Federal R&D program
- Applicability
- Applicable to decisions about the stated program, policy, standard, or development context; not evidence of clinical benefit beyond the cited scope.
- Confidence for the stated claim
- High
- Freshness
- Current
- Record date
- 2026-02-24
- Source updated
- 2026-02-24
- Last verified
- 2026-09-03
- Review due
- 2026-10-03 or sooner if the cited source changes.
- Version
- 1.1
- Revision state
- Version 1.1 records the September 3, 2026 re-verification, adds current PROSPR program and award-directory sources, and clarifies that the seven awards, funding ceiling, and continued funding are milestone-contingent rather than evidence of results.
Evidence record fields
- Claim supported
- PROSPR funds seven teams to build healthspan measures and accelerated trials, with up to $144M over five years.
- Source type and design
- Federal R&D program
- Population and setting
- Not a participant-level clinical-study population in this source type. The program, policy, regulatory, standards, or research context described by the cited source.
- Intervention/exposure and comparator
- Not evaluated as a comparative intervention or exposure in the cited administrative or program source. No comparator is reported for this source-bounded claim.
- Outcome or endpoint
- The program, policy, regulatory, standards, or development state stated in the claim supported; no clinical outcome is inferred.
- Follow-up duration
- No clinical follow-up duration is reported for this source-bounded claim.
- Effect estimate and uncertainty
- No clinical effect estimate is reported. No statistical uncertainty estimate is reported; uncertainty is bounded through the source scope and stated limitations.
- Harms/adverse events
- No harms or adverse-event analysis is reported for this source-bounded administrative or program claim.
- Missing data and attrition
- Not reported; this record does not analyze participant-level data. Not applicable or not reported; no longitudinal participant cohort is analyzed.
- Bias/limitations
- The seven awards and funding ceiling are program facts, not evidence that the full ceiling will be paid or that an endpoint or intervention works. Continued funding is milestone-contingent, and the work remains investigational.
- Applicability/generalizability
- Applicable to decisions about the stated program, policy, standard, or development context; not evidence of clinical benefit beyond the cited scope.
- Funding/conflicts
- Funding or sponsorship is recorded only where the cited source and claim state it; otherwise it is not assessed in this record. No conflict-of-interest assessment is reported for this administrative or program-source record.
- Replication or corroboration
- The administrative or program claim is anchored to the cited authoritative source; independent clinical replication is not implied.
- Decision use
- Use as source-bounded context for Researchers, Innovators, Funders/investors, Policymakers; do not use as stand-alone evidence of safety, efficacy, coverage, endorsement, or scaled adoption.
- Last reviewed / review due
- Last reviewed 2026-09-03; review due 2026-10-03 or sooner if the cited source changes.
For this decision
Researchers · Innovators · Funders/investors · Policymakers